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Fig. 5. Disruption of RA signaling inhibits intracellular Ca2+ signaling in the kidney field. (A) PMT traces from single pronephric territories dissected from control embryos injected with GFP–aequorin mRNA (Control) and embryos injected with GFP-æquorin mRNA plus Cyp26 mRNA (Cyp26). Representative data of pairs of territories measured simultaneously from three independent experiments. (B) Mean6s.e.m. number of Ca2+ transients during 4 h in control and Cyp26 conditions calculated for three independent pairs of experiments. Disruption of RA signaling significantly reduces the number of Ca2+ transients (P50.008, paired Student’s t-test).

Image published in: Futel M et al. (2015)

Copyright © 2015. Image reproduced with permission of the Publisher, The Company of Biologists Ltd.

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