XB-IMG-138288
Xenbase Image ID: 138288
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Figure 1. Nucleotide and deduced amino acid sequences of the coding regions ofxenopus Kv2.1 and Kv2.2 cDNAs. Amino acid and nucleotide positions
are indicated in the right-hand column. The putative transmembrane domains (SI-S6) and the pore region (P) are overlined. A putative glycosylation site
between S3 and S4 is indicated by a star. Consensus CAMP phosphorylation sites are indicated by filled circles above the amino acid position. The Xenopus
Kv2.1 and Kv2.2 nucleotide sequences have been assigned Genbank accession numbers U20342 and U20343, respectively. A, Nucleotide and amino acid
sequence of XShabY (Xenopus Kv2.1). Dashes appear under the region spanned by the pXb4 PCR product. pXb4 nucleotide sequences that differ from
Kv2.1 sites are shown below the corresponding Kv2.1 nucleotides (nucleotides 762 and 1056). B, Nucleotide and amino acid sequence of XShab12 (Xenopus Kv2.2). Dashes appear under the region spanned by the pXb3 PCR product. pXb3 nucleotide sequences that differ from Kv2.2 are shown
underneath the corresponding Kv2.2 nucleotides. Except for one nucleotide change at position 854, all nucleotide changes occur in the third codon
position. A tyrosine phosphorylation site is marked by a triangle. Although two of three CAMP phosphorylation sites are conserved between Kv2.1 and
Kv2.2, the putative tyrosine phosphorylation site is unique to Kv2.2 (amino acid 512) Image published in: Burger C and Ribera AB (1996) Copyright © 1996. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |