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XB-IMG-139022

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Fig. 3. Real-time responses of myeloid cells to mechanical injury. (A) Schematic representation of the different wounding methods used on transgenic X. laevis larvae. (B) Average speed was calculated from the lurp+ cell population in at least 3 different experiments for each condition 1 h after wounding. One-way analysis of the variance (ANOVA) and Tukey׳s Multiple Comparison Test were used for statistical analysis. *p<0.05; **p<0.01; ***p<0.001. (C) Single channel confocal projection and best in focus transmitted light images after melanophore ablation injury. The LASER pulse was directed at the area denoted 1B (red circle). The melanophore (red circle), the intersomitic space (colored yellow mask) and some muscle fibers (colored red mask) are highlighted for reference. See supplementary video 9, associated with this panel. (D) Single channel confocal projection (gray scale) of adjacent myeloid cells migrating towards the wound stimulus, projecting lamellipodia denoted by red arrows.

Image published in: Paredes R et al. (2015)

© 2015 The Authors. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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