Xenbase Image ID: 139087

Figure 3. bCNGA1-Dend2 is excluded from the PM domains proximal to the axoneme and at the bottom of OS. A, bCNGA1-Dend2 does not localize in the proximity of the axoneme (arrowheads); bCNGA1-Dend2 (green) was colabeled with anti-acetylated tubulin (red). B, C, The localization of bCNGA1 in the rod cells with and without IS, respectively. bCNGA1-Dend2 localization forms an aberrant closed shape (B, left, asterisk) only in the OS detached from the IS as revealed by DIC image (B, right, asterisk). In C, F-actin was labeled with fluorescent phalloidin (red) to reveal IS structures, which are not attached to OS with aberrant localization of bCNGA1-Dend2 (arrowhead). Images are either from fixed retina (A, C) or live and unfixed retina (B). Animals were 14 d old. Scale bars: 5 μm. Image published in: Nemet I et al. (2014) Copyright © 2014. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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