Xenbase Image ID: 139679

Fig. S3. Depletion of Lrig3 by L3MO inhibited NC formation. Embryos were injected with 15 ng L3MO into one dorsal blastomere at the four-cell stage. The expression of the retinal marker Rx2A (A-A′′) and the NC markers Ap2a (B-B′′), Traf4 (C-C′′) and Twist (D-D′′) was examined at the late neurula stage; the injection side was visualized by lacZ staining. Rx2a was modestly decreased on the injected side (48%, 13 of 27 embryos). Traf4 (80%, 16 of 20), Twist (83%, 25 of 30), and Ap2a (80%, 16 of 20) were strongly inhibited. Image published in: Zhao H et al. (2008) Copyright © 2008. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

Return to previous page