Xenbase Image ID: 139692

Fig. 4. Inhibition of ErbB signaling blocked C&E in early Xenopus embryos. RNA encoding nuclear βGal (0.1 ng) was coinjected with DN-ErbB RNAs (2 ng) or 20 ng control-MO or ErbB4-MO into DMZ of four-cell stage embryos. The pattern of dorsal cell distribution was examined by staining of the injected embryos at gastrula or neurula stages with the Red Gal substrate. While the labeled cells formed a long and narrow stripe along the dorsal midline in control or control-MO-injected embryos, cells from DN-ErbB- or ErbB4-MO-expressing embryos showed a much wider and shorter distribution. Image published in: Nie S and Chang C (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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