XB-IMG-139697
Xenbase Image ID: 139697
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Fig. 9. ErbB signaling controlled cell spreading on fibronectin. (A) Cells from control DMZ explants spread upon binding to FN, but cells from explants injected with DN-ErbBs or ErbB4-MO showed reduced ability to spread. (B) Quantification of cell spreading on FN-coated coverslip. Control samples showed 58% of cells spreading on FN, but 35%, 34%, 27% and 33% of cells expressing DN-EGFR, DN-ErbB2, DN-ErbB3 and DN-ErbB4 spread on FN respectively. 30% of cells expressing ErbB4-MO spread, and the number increased to 52% when human ErbB4 was coexpressed with the MO. Image published in: Nie S and Chang C (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |