Xenbase Image ID: 139753

Figure 2. The K346T mutation increases Kir2.1 currents. Sample current families recorded from oocytes expressing WT (A) or K346T (B) mRNA (the pulse protocol is shown as inset). (C) I–V relationships for WT (white circles, 3 ng) and K346T (black circles, 3 ng) channels. (D) Current amplitudes recorded at −100 mV from cells injected with the indicated mRNAs whose amounts are reported in brackets (mean ± SEM; n = 120; *P < 0.05; **P < 0.01). (E) Current amplitudes recorded at −60 mV for WT (white circles) and K346T (black circles) channels and plotted as a function of time after mRNA injection (mean ± SEM; n = 6). Image published in: Ambrosini E et al. (2014) © The Author 2014. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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