Xenbase Image ID: 139801

Figure 3. ptf1a/p48-targeted X. laevis G0 tadpoles showed reduction of pdip expression. Whole-mount in situ hybridization analyses of pdip expression (stage 42). Ventral-lateral view, head to the left. (A, B) Wild type X. laevis tadpoles. (C, E) Severe reduction. (D, F) Mild reduction. (G, I) Severe reduction. (H, J) Mild reduction. (K, N) Almost complete absence. (L, O) Severe reduction. (M, P) Mild reduction. Image published in: Wang F et al. (2015) © Wang et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue pdia2.L pdi, pdip, XPDIp X. laevis Throughout NF stage 42 pancreas ventral pancreatic bud dorsal pancreatic bud Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + ptf1a gRNA2/3 CRISPR + NF43 (in situ hybridization) Fig. 3 LMOP Expression Phenotype decreased amount pdia2.L expression in dorsal pancreatic bud decreased amount pdia2.L expression in ventral pancreatic bud Xla Wt + ptf1a gRNA2 CRISPR + NF43 (in situ hybridization) Fig. 3. CDEF Expression Phenotype decreased amount pdia2.L expression in dorsal pancreatic bud decreased amount pdia2.L expression in ventral pancreatic bud Xla Wt + ptf1a gRNA3 CRISPR + NF43 (in situ hybridization) Fig. 3. GHIJ Expression Phenotype decreased amount pdia2.L expression in dorsal pancreatic bud decreased amount pdia2.L expression in ventral pancreatic bud Xla Wt + ptf1a gRNA2/3 CRISPR + NF43 (in situ hybridization) Fig.3 KN Expression Phenotype absent pdia2.L expression in dorsal pancreatic bud absent pdia2.L expression in ventral pancreatic bud Larger Image Printer Friendly View

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