Xenbase Image ID: 139803

Figure 5. Simultaneous disruption of two  X. laevis tyrosinase  homeologs leads to albinism in G0 tadpoles (stage 42). Lateral view, head to the left. (A, D) Almost full albinism. (B, E) Severe inhibition of pigmentation. (C, F) Almost normal. (G, J) Wild type. (H, I, K, L) Almost normal. Image published in: Wang F et al. (2015) © Wang et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Experiment + Assay Source Phenotypes and Disease Xla wt + tyr gRNA 14/16 CRISPR + NF42 (whole-mount microscopy) Fig. 5 AD Anatomical Phenotype absent pigment cell decreased pigmentation in the eye Disease ocular albinism 1 Xla wt + tyr gRNA 14/16 CRISPR + NF42 (whole-mount microscopy) Fig. 5 BCEF Anatomical Phenotype decreased pigmentation in the epidermis decreased pigmentation in the eye decreased pigmentation in the head decreased pigmentation in the whole organism Larger Image Printer Friendly View

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