XB-IMG-140041
Xenbase Image ID: 140041
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Figure 1 In X. tropicalis, human, and mouse, the consensus NRSE
motifs share sequence similarity and the majority of the NRSE sites
are farther than 20 kb from a gene, with a single copy per gene.
A. Sequence logos of the consensus NRSE motif derived from 32
bona fide mouse REST target genes ([26], top panel), from 1301
human NRSE motifs ([25], middle panel), and from 742 X. tropicalis
NRSE motifs (bottom panel). Arrowheads mark the differences
between the Xenopus and human consensus motifs. B. In all three
vertebrate genomes, ~ 65% of the motifs are located farther than 20
kb from a gene. C. 80% to 90% of the putative REST target genes in
three organisms have a single NRSE motif within 100 kb of a gene. Image published in: Saritas-Yildirim B et al. (2015) © Saritas-Yildirim et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |