Xenbase Image ID: 144158

Fig. 4. ATP4a-dependent Wnt signaling acts downstream of Notch in skin foxj1 induction. (A–D) foxj1 was stained in uninjected control (uninj.) embryos (A), as well as manipulated embryos (injected side shown in B–D). (B) Inhibition of Notch by injection of Su(H)-DBM mRNA increased foxj1 expression, which remained dependent on ATP4a (C) and Wnt/β-catenin (β-cat.; D). (E) Quantification of results. Staining intensity on the injected (right) side was compared to the uninjected (left) control side and quantified as right/injected side stronger, weaker or equal to the control side (G) (a, anterior; d, dorsal; n, number of embryos; ns, not significant; p, posterior; st., stage; v, ventral). Image published in: Walentek P et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue foxj1.L foxj1-a, foxj1-b, hfh-4, hfh4, xfoxj1 X. laevis Throughout NF stage 17 epidermis ciliated epidermal cell Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + dnrbpj + NF15-18 (in situ hybridization) Fig. 4 B E Expression Phenotype increased amount foxj1.L expression in epidermis Larger Image Printer Friendly View

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