Xenbase Image ID: 144197

Figure 3 A role for Prdm12 in sensory neuron development. (a) Whole-mount in situ hybridization of mouse embryos at E9.0 (left) identified expression of Prdm12 in neural folds (black arrowhead), which coincided with the earliest stage of neural crest cell delamination and migration (white arrowhead). Figure 3 A role for Prdm12 in sensory neuron development. (a) Whole-mount in situ hybridization of mouse embryos at E9.0 (left) identified expression of Prdm12 in neural folds (black arrowhead), which coincided with the earliest stage of neural crest cell delamination and migration (white arrowhead). In situ hybridization of whole embryos (middle) and transverse sections of cervical spinal cord (right) at E10.5 showed strong Prdm12 expression in DRG (black arrowheads). Scale bars: left, 250 μm; middle, 500 μm; right, 100 μm. (b) RT-PCR analysis confirmed Prdm12 expression throughout the whole period of DRG development and sensory neuron differentiation (E9.5–P14) and in mature DRG (P56). Image published in: Auer-Grumbach M et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher, Macmillan Publishers Ltd. Larger Image Printer Friendly View

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