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Figure 7. TCF/Lef-Dependent Transcription Is Required for Neural Potential of Retinal Progenitors Rx:ΔN-Tcf3-GFP transgenic embryos (stage 23) show normal expression of Rx and En (B) and the retinal progenitor markers Pax6 (D), Six6 (F), and Chx10 (H) compared to control Rx:GFP transgenic embryos (A, C, E, and G). Rx:ΔN-Tcf3-GFP transgenic embryos show loss of both Sox2 and Xdelta-1 expression in the retinal domain (bracket in [J] and [L]) as compared to control transgenic embryos (Rx:GFP) (I and K). Image published in: Van Raay TJ et al. (2005) Copyright © 2005. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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