Xenbase Image ID: 144670

Fig. 2. Voltage-dependent potassium 1.3 (Kv1.3)–like subunits are expressed in the Xenopus retina. Transverse sections through the Xenopus retina at different developmental stages were immunostained with a rabbit antibody against the C-terminus of the human Kv1.3 subunit. A: At stage 32, cells in the neuroepithelium of the retina and brain are immunopositive. B: At stage 37/38, retinal ganglion cells (RGCs) and their processes along the vitreal surface are labelled, as are the inner and outer plexiform layers (IPL and OPL) and the ciliary marginal zone (CMZ). C,E: By stage 40, the optic nerve head and optic nerve are brightly labelled. D: Almost no labelling is observed when the Kv1.3 subunit antibody is preincubated with a control Kv1.3 subunit peptide antigen. Similar low power sections are shown in C and D. Br, brain; D, dorsal; L, lens; NP, neuropil; on, optic nerve; onh, optic nerve head; PE, pigmented epithelium; RGCL, retinal ganglion cell layer; V, ventral; vs, vitreal surface. Scale bar 50 m for A, B, and E and 100 m for C and D. Image published in: Pollock NS et al. (2002) Copyright © 2002. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue kcna3.S k(v)1.3, kv1.3 X. laevis Throughout NF stage 32 lens placode kcna3.S k(v)1.3, kv1.3 X. laevis Sometime during NF stage 37 and 38 to NF stage 40 retinal ganglion cell globe ciliary marginal zone optic nerve optic disc retina retinal inner plexiform layer retinal outer plexiform layer retinal ganglion cell layer Image source: Published Larger Image Printer Friendly View

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