Xenbase Image ID: 144675

Fig. 7. Voltage-dependent potassium (Kv) subunits are differentially expressed in developing Xenopus retinal ganglion cell (RGC) growth cones. Stage 24 eye primordia were grown in culture for 24–48 hours and labelled with various Kv subunit antibodies. A: Phase micrograph of the same RGC axons shown in B. Arrowhead points to a filopodia. B: The Kv1.3 channel antibody labels the axon abundantly, but not the body of the growth cone, nor the filopodia or lamellipodia. C: The Kv1.5 antibody labels the RGC axon and the entire growth cone, including the filopodia (arrowhead). D: The Kv4.2 antibody labels the RGC axon and growth cone in a punctate manner. Scale bar 16 m for A–D. Image published in: Pollock NS et al. (2002) Copyright © 2002. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue kcnd2 kv4.2, LOC108711141, LOC108712359 X. tropicalis Throughout NF stage 24 retinal ganglion cell axon growth cone kcna4.L k(v)1.4, Kv1.4, LOC108713813 X. laevis Throughout NF stage 24 retinal ganglion cell axon growth cone kcna3.S k(v)1.3, kv1.3 X. laevis Throughout NF stage 24 retinal ganglion cell axon Image source: Published Larger Image Printer Friendly View

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