XB-IMG-144874
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Figure 4. Time course for the mRNA expression of Mrf transcriptions factors in chicken embryos from HH10-E4; orientation of specimen and frames indicating the onset of expression as in Figure 3. Gene names and developmental stages are displayed as in Figure 3, Abbreviations as in Figures 1, 3 and: hy, hyoid arch. Myf5 and MyoD indicate the myogenic commitment of precursor cells and are expressed in developing craniofacial muscle anlagen from HH13/14 (Myf5) and HH16 (MyoD) onwards, i.e., significantly before the onset of Pax7. Expression of Myogenin (MyoG/Mgn) indicates the entry of cells into muscle differentiation and commences at E3.5-4, i.e., about the same time as Pax7 (compare with Figure 1). Image published in: Nogueira JM et al. (2015) Copyright © 2015 Meireles Nogueira, Hawrot, Sharpe, Noble, Wood, Jorge, Goldhamer, Kardon and Dietrich. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |