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Figure 5. Time course in chicken embryos from HH10-E4 for markers indicating the cohesion of muscle anlagen (Cadherin 4–mRNA expression) and terminal differentiation [Troponin I 1 (Tnni1)–mRNA expression; sarcomeric Myosin–MF20 antibody staining]. Orientation of specimen and frames indicating the onset of expression as in Figures 3, 4; abbreviations as in Figures 1, 3, 4. The time course of Cadherin 4 expression resembles that of MyoD, and Tnni1 expression commences in many craniofacial muscle anlagen E3, i.e., both are expressed before or at the onset of Pax7 expression. Sarcomeric Myosins can be detected at E3.5-4, simultaneous to the onset of Pax7. Image published in: Nogueira JM et al. (2015) Copyright © 2015 Meireles Nogueira, Hawrot, Sharpe, Noble, Wood, Jorge, Goldhamer, Kardon and Dietrich. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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