Xenbase Image ID: 144876

Figure 6. Time course for the mRNA expression of trunk pre-myogenic genes; embryos are displayed and annotated as in Figures 3–5. Abbreviations as before and: na, nasal pit. (A–E) Pax3 labels the central nervous system, the frontonasal neural crest, the trigeminal ganglion, the somites and the somite-derived hypobranchial and limb muscle precursors, but remains absent from genuine craniofacial muscle anlagen. (F–J) Paraxis expression overlaps with that of Pax3 and 7 in the somite-derived muscle precursors and in the frontonasal crest. Similar to Pax7, Paraxis is also expressed in the lateral rectus eye muscle, but is absent from all other craniofacial muscles. Six1 (K–O) and Eya1 (P–T) are expressed in the head mesoderm before and at HH10. From that stage onwards mesoderm expression becomes somewhat obscured by the overlying expression in neural crest cells. However, Six1 (but not Eya1) remains detectable in craniofacial muscle anlagen. Image published in: Nogueira JM et al. (2015) Copyright © 2015 Meireles Nogueira, Hawrot, Sharpe, Noble, Wood, Jorge, Goldhamer, Kardon and Dietrich. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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