Xenbase Image ID: 145169

Fig. 6. ERF or ETV3L knockdown rescues the extra/ectopic neuron phenotype generated by TTNPB. All embryos were injected unilaterally at the two- or four-cell stage. The injected side is indicated by the magenta β-gal mRNA lineage tracer. Embryos were treated at stage 7/8 with TTNPB or control vehicle (0.1% ethanol). (A,B) 10 ng control MO does not change expression of N-tubulin (NC, no change). (C,D) 10 ng Erf MO rescues (96%) the TTNPB extra/ectopic neuron phenotype (NT, no tubulin). (E,F) 20 ng Etv3l MO completely rescues (100%) the TTNPB phenotype. Embryos are shown in dorsal view with anterior at the bottom, at stage 14. Image published in: Janesick A et al. (2013) Copyright © 2013. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 18 neuron Image source: Published Larger Image Printer Friendly View

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