XB-IMG-145184
Xenbase Image ID: 145184
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Fig. S12. ERF or ETV3L knockdown increases proliferation in the neural plate. Embryos were injected unilaterally at the 2-
or 4-cell stage. (A,B,D,E,G,H) The injected side is indicated by the red fluorescent lineage tracer. Representative photographs in
brightfield (A,D,G) and fluorescence (B,E,H) are shown. (C,F,I) Quantitation of PCNA staining for all embryos in the experiment
is provided in bar graphs. Embryos are shown in dorsal view at stage 14; anterior is at the bottom. (A-C) Embryos injected with 10
ng control MO showed no significant difference in the number of PCNA nuclei on the injected versus the uninjected side (n=41;
P=0.776). (D-F) Embryos injected with 10 ng Erf MO showed an increased number of PCNA nuclei on the injected side (n=45;
P=0.0009). (G-I) Embryos injected with 10 ng Etv3l MO showed an increased number of PCNA nuclei on the injected side (n=46;
P=0.0009). Image published in: Janesick A et al. (2013) Copyright © 2013. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
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