XB-IMG-145285
Xenbase Image ID: 145285
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Fig. 1. Amino acid sequences of xrds36, xrds35 and xrds38 aligned with mouse rds/peripherin and rom-1. The cytoplasmic, membranespanning,
and intradiscal domains are indicated by C#, M# and D#, respectively. Identical residues are indicated by the shaded boxes. Amino
acids affected by point mutations in the human RDS-mediated inherited retinal dystrophies are indicated by black dots. The Y character above
Asn residue #229 denotes the position of N-linked glycosylation. Notice the high degree of sequence conservation and preponderance of
mutant substitutions within the D2 loop. Nucleotide sequences for xrds38, xrds36 and xrds35 were deposited in GenBank under accession
numbers: L79915, L79914, L79913, respectively. Image published in: Kedzierski W et al. (1996) Copyright © 1996. Image reproduced with permission of the Publisher, The Company of Biologists Ltd. Larger Image Printer Friendly View |