Xenbase Image ID: 145476

FIG. 3. Exposure to lithium at the late-blastula stage results in the loss of both forebrain and midbram. Untreated embryos (A) or embryos treated with lithium at stage 10 (B) or 9 (C) were cultured to stage 32 and hybridized with digoxygenin-labeled Xotx2 riboprobes. Staining of the telencephalon (open black arrow), the ventral dieneephalon (open white arrow), and the midbrain (between filled arrows) is indicated Image published in: Fredieu JR et al. (1997) Copyright © 1997. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue otx2.S otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Throughout NF stage 32   Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + LiCl + NF29/30 (in situ hybridization) Fig.3.b Anatomical Phenotype wholly posteriorized embryo Expression Phenotype decreased amount otx2.S expression in head Xla Wt + LiCl + NF29/30 (in situ hybridization) Fig.3.c Expression Phenotype decreased amount otx2.S expression in head Larger Image Printer Friendly View

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