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XB-IMG-145478

Xenbase Image ID: 145478

FIG. 5. Exposure to lithium during gastrulation or misexpresslon of Xwnt-8 retards involution of the dorsoantenor mesoderm. Mldsagittal confocal images of an untreated embryo (A) and of embryos treated with lithium at stage 12 (B), 11 (C), 10 (D), or 9 (E) or made to misexpress Xwnt-8 in the dorsal mesoderm (F) and then cultured to stage 13. Arrowhead in each panel marks the position of the yolk plug while the archenteron is denoted by an arrow and the blastocoel by an asterisk. Dorsal is toward the top of the micrograph.

Image published in: Fredieu JR et al. (1997)

Copyright © 1997. Image reproduced with permission of the Publisher, Elsevier B. V.

Experiment + Assay Source Phenotypes and Disease
Xla Wt + LiCl + NF13 (morphology) Fig.5.b
Anatomical Phenotype
decreased length of archenteron
Xla Wt + LiCl + NF13 (morphology) Fig.5.c
Anatomical Phenotype
abnormally delayed closure of blastopore
decreased length of archenteron
Xla Wt + LiCl + NF13 (morphology) Fig.5.d
Anatomical Phenotype
abnormally delayed closure of blastopore
decreased length of archenteron
Xla Wt + LiCl + NF13 (morphology) Fig.5.e
Anatomical Phenotype
abnormally delayed closure of blastopore
abnormally increased volume of blastocoel
absent archenteron
Xla Wt + wnt8b + NF13 (morphology) Fig.5.f
Anatomical Phenotype
abnormally delayed closure of blastopore
decreased length of archenteron

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