XB-IMG-145972
Xenbase Image ID: 145972
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Fig 4. In vivo requirement of Pkdcc1 and Pkdcc2 during early development.
(A-I”) Four cell stages were injected either (A, D, G) dorsally or (B-C, E-F”, H-I”) unilaterally with (D-F”) pkdcc1Mo, (G-I”) pkdcc2Mo or (A-C) coMo and analysed at (A, D, G) stage 13, (B, E, H) 15 or (C, F-F”, I-I”) 18/19. Injection of pkdcc1Mo and pkdcc2Mo caused (D, G) gastrulation and (E-F, H-I) neural tube closure defects that were not observed in (A-C) coMo injected embryos. (F’-F”, I’-I”) Magnification of the stage 18/19 pkdcc1Mo and pkdcc2Mo unilaterally injected embryos. Yellow and red arrows show the delay of neural fold formation. A, anterior; P, posterior; D, dorsal; V, ventral; inj, injected side; co, uninjected side. Image published in: Vitorino M et al. (2015) Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license
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