Xenbase Image ID: 146126

Fig. 3. Dystroglycan-depleted cells failed to integrate into the notochord. At the four-cell stage, the two left blastomeres were injected with C-MO or Dg-MO (33†ng) and ras-GFP mRNAs, the two right blastomeres were injected with RLDx as internal controls. Transverse sections at stages 15 (A-F) and 32 (G-L) are shown. (A-C,G-I) Controls. Notochordal cells containing C-MO (green) or RLDx (red) are implicated equally in notochord formation. The axis of symmetry is indicated by the dotted lines. (D-F,J-L) Dg-MO cells (green) are not integrated into the notochord. NC, notochord; NT, neural tube; S, somite. Scale bars: 25†μm. Image published in: Buisson N et al. (2014) Copyright © 2014. Image reproduced with permission of the Publisher. Larger Image Printer Friendly View

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