Xenbase Image ID: 146126

Fig. 3. Dystroglycan-depleted cells failed to integrate into the notochord. At the four-cell stage, the two left blastomeres were injected with C-MO or Dg-MO (33 ng) and ras-GFP mRNAs, the two right blastomeres were injected with RLDx as internal controls. Transverse sections at stages 15 (A-F) and 32 (G-L) are shown. (A-C,G-I) Controls. Notochordal cells containing C-MO (green) or RLDx (red) are implicated equally in notochord formation. The axis of symmetry is indicated by the dotted lines. (D-F,J-L) Dg-MO cells (green) are not integrated into the notochord. NC, notochord; NT, neural tube; S, somite. Scale bars: 25 μm. Image published in: Buisson N et al. (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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