Fig. 1. Expression of the PRC2 core components during early Xenopus development. Eed, Ezh2 and Suz12 are expressed similarly in early Xenopus embryos. Their transcripts are detected in the pan- mesoderm in late blastulae and early gastrulae embryos, but are shifted to dorsal mesodermal and dorsal ectodermal cells at late gastrula stages. During neurulation, their RNAs are located in neural and neural crest cells. At tailbud and tadpole stages, these genes are expressed in neural, sensory organs and migrating neural crest cells. Image published in: Tien CL et al. (2015) Copyright © 2015. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.Gene Synonyms Species Stage(s) Tissue eed.L eed-a, eed-b, MGC82196, wait1, Xeed X. laevis Throughout NF stage 10 involuted dorsal mesoderm eed.L eed-a, eed-b, MGC82196, wait1, Xeed X. laevis Throughout NF stage 11 mesoderm involuted dorsal mesoderm eed.L eed-a, eed-b, MGC82196, wait1, Xeed X. laevis Throughout NF stage 18 neural crest cranial neural crest optic vesicle eed.L eed-a, eed-b, MGC82196, wait1, Xeed X. laevis Throughout NF stage 27 optic vesicle otic vesicle neural crest cranial neural crest hyoid crest mandibular crest olfactory placode eed.L eed-a, eed-b, MGC82196, wait1, Xeed X. laevis Throughout NF stage 35 and 36 eye otic vesicle midbrain-hindbrain boundary neural crest cranial neural crest branchial arch hyoid arch mandibular arch chordoneural hinge tail bud lateral line primordium ezh2.L enx-1, enx1, ezh1, ezh2-a, ezh2-b, kmt6, xez, xtezh2 X. laevis Throughout NF stage 10 involuted dorsal mesoderm ezh2.L enx-1, enx1, ezh1, ezh2-a, ezh2-b, kmt6, xez, xtezh2 X. laevis Throughout NF stage 11 mesoderm involuted dorsal mesoderm ezh2.L enx-1, enx1, ezh1, ezh2-a, ezh2-b, kmt6, xez, xtezh2 X. laevis Throughout NF stage 18 neural crest cranial neural crest optic vesicle trunk neural crest ezh2.L enx-1, enx1, ezh1, ezh2-a, ezh2-b, kmt6, xez, xtezh2 X. laevis Throughout NF stage 27 otic vesicle optic vesicle neural crest hyoid crest tail region tail bud ezh2.L enx-1, enx1, ezh1, ezh2-a, ezh2-b, kmt6, xez, xtezh2 X. laevis Throughout NF stage 35 and 36 eye otic vesicle midbrain-hindbrain boundary olfactory placode lateral line primordium hyoid arch branchial arch mandibular arch chordoneural hinge tail bud tail region suz12.S chet9, jjaz1, Xsuz12 X. laevis Throughout NF stage 10 mesoderm suz12.S chet9, jjaz1, Xsuz12 X. laevis Throughout NF stage 11 mesoderm involuted dorsal mesoderm suz12.S chet9, jjaz1, Xsuz12 X. laevis Throughout NF stage 18 neural crest cranial neural crest trunk neural crest optic vesicle suz12.S chet9, jjaz1, Xsuz12 X. laevis Throughout NF stage 27 optic vesicle olfactory placode neural crest cranial neural crest mandibular crest hyoid crest tail bud tail region suz12.S chet9, jjaz1, Xsuz12 X. laevis Throughout NF stage 35 and 36 neural crest cranial neural crest mandibular crest hyoid crest hyoid arch mandibular arch otic vesicle eye midbrain-hindbrain boundary olfactory placode tail bud chordoneural hinge tail region tail lateral line lateral line primordium
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