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Figure 1—figure supplement 1. Yap, Taz [=wwtr1] and Tead expression. (A) In situ hybridization analysis of Yap expression on stage 24–25 (left), 26–27 (middle) and stage 35 (right) retinal sections. Yap is expressed in the presumptive neural retina (NR) of the optic vesicle but is more strongly detected in the presumptive retinal pigmented epithelium (RPE), consistently with previous data in fish (Miesfeld and Link, 2014). It also labels the RPE/NR border region (delineated with dotted lines), which is believed to give rise to the CMZ (El Yakoubi et al., 2012). At latter stages, Yap gets restricted to the ciliary margin (black arrows). (B, C) In situ hybridization analysis of Taz (B), Tead1 and Tead2 (C) expression on stage 40 retinal sections. Images on the right are higher magnifications of the ciliary margin. Scale bar = 40 µm. DOI: http://dx.doi.org/10.7554/eLife.08488.004 Image published in: Cabochette P et al. (2015) © 2015, Cabochette et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue yap1.S xyap, yap, yap2, yap65, yki X. laevis Sometime during NF stage 24 to NF stage 35 and 36 optic vesicle retinal pigmented epithelium retinal neural layer ciliary marginal zone wwtr1.L taz, xtTAZ X. laevis Throughout NF stage 40 ciliary marginal zone tead1.S tef-1, xlNTEF-1, XNTEF-1, xtead1 X. laevis Throughout NF stage 40 ciliary marginal zone retinal stem cell region tead4.S tead2, xdtef-1, xlDTEF-1 X. laevis Throughout NF stage 40 ciliary marginal zone retinal stem cell region Image source: Published Larger Image Printer Friendly View

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