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Figure 8. Analysis on the expression of genes responsible for germ layer formation in response to knockdown of Klf factors. A: Effects of knockdown of Klf factors on gene expression. The doses of each injected MO were the same as those in Figure 6B–J. All embryos are shown as vegetal view with the dorsal being placed up or as dorsal view with the animal pole being orientated up. B: Ratios of embryos with normal or disturbed transcription among the total numbers (n) of injected embryos.Download figure to PowerPoint
Image published in: Gao Y et al. (2015)
Copyright © 2015. Image reproduced with permission of the Publisher, John Wiley & Sons.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|
| dkk1.L | dickkopf-1, Dickkopf1, dkk, dkk-1, Xdkk-1, xdkk1 | X. laevis | Throughout NF stage 10.5 | upper blastopore lip
involuted dorsal mesoderm
dorsal marginal zone
| | cer1.L | cer, cer-1, Cerberus, dand4, LOC108713989, tCerberus, xcer, xcer-1, xcer1 | X. laevis | Throughout NF stage 10.5 | upper blastopore lip
dorsal marginal zone
involuting marginal zone
sub-blastoporal endoderm
endomesoderm
| | chrd.L | chd, chordin, chrd.1, LOC108716939, X-chordin | X. laevis | Throughout NF stage 10.5 | upper blastopore lip
involuting marginal zone
dorsal marginal zone
involuted dorsal mesoderm
presumptive axial mesoderm
| | gsc.L | goosecoid, gsc-a, gsc-b, Xgsc | X. laevis | Throughout NF stage 10.5 | upper blastopore lip
dorsal marginal zone
involuted dorsal mesoderm
endomesoderm
involuting marginal zone
| | wnt8a.L | wnt-8, wnt8, Xwnt-8, Xwnt8 | X. laevis | Throughout NF stage 10.5 | lower blastopore lip
endomesoderm
endoderm
suprablastoporal endoderm
sub-blastoporal endoderm
| | nodal5.L | nr5, xnr5, xnr5-2 | X. laevis | Throughout NF stage 10.5 | upper blastopore lip
involuted dorsal mesoderm
endomesoderm
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