XB-IMG-147762
Xenbase Image ID: 147762
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Fig. 1. (a) Embryos injected with FGF-8/LacZ RNA show abundant ectopic neurogenesis. (b) Compared with FGF-8, eFGF RNA had a very weak effect on neurogenesis. Although some ectopic N-tubulin formed, the percentage of the affected embryos was lower (see text) and the phenotype less severe. The posterior elongation seen in the second eFGF panel was observed in approximately 50% of the high dose eFGF RNA injected embryos (n = 25) and was not seen in FGF-8 RNA-injected embryos. (c) Comparison of FGF-8 activity to that of noggin, RA, and X-ngnr1 (see text). Black arrows point to the interstripe region. All panels show expression of N-tubulin with the exception of the inset (XSox3). In all panels anterior is to the left and most panels show dorsal views, lateral views are indicated. Image published in: Hardcastle Z et al. (2000) Copyright © 2000. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |