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Fig. 4. The Dishevelled-dependent WNT/PCP pathway is not required for GATA4-mediated cardiogenesis. Injection of Dishevelled (Dsh) δPDZ dominant-negative construct, which inhibits both canonical and PCP WNT pathways, does not alter induction of the cardiac marker MLC2 by GATA4 and Cerberus. Similarly, Dishevelled DEP+, a PCP pathway-specific dominant-negative construct, does not affect induction of MLC2 by GATA4. Image published in: Latinkić BV et al. (2003) Copyright © 2003. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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