Xenbase Image ID: 148427

Fig. 5. Cell proliferation in pou5f3.2-injected embryos. (A) Cell division in the marginal zone of St.10.5 embryo injected with 800 pg GFP RNA, 800 pg pou5f3.2 RNA or 4.2 ng pou5f3.2MO. M-phase cells were detected as red fluorescence by immunostaining with anti-PH3 antibody. Nuclei were stained with Hoechst. (B) Mitotic index in the marginal zone of St.10.5 embryo injected with GFP RNA, pou5f3.2 RNA or pou5f3.2MO. Bar indicates the standard deviation calculated from more than seven samples. Image published in: Nishitani E et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue h3-3a.L h3.3, h3.3a, h3f3a X. laevis Throughout NF stage 10.5 mitotic cell Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + pou3f2 + NF10.5 (immunohistochemistry) fig.5.a, b Anatomical Phenotype increased cell population proliferation in marginal zone Xla Wt + pou5f3.2 MO + NF10.5 (morphology) fig.5.a, b Xla Wt + pou5f3.2 MO + NF10.5 (morphology) Fig.5.a,b Anatomical Phenotype decreased cell population proliferation in marginal zone Larger Image Printer Friendly View

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