Xenbase Image ID: 148644

Figure 8. Genomic control of cellular functions in developing multiciliated cells. Left panels (‘Gene Expression’) illustrate genetic controls as reported in Figure 2, Figure 2—figure supplements 2–4, and Supplementary file 1A–C. Solid red lines in this figure indicate direct control of transcription by Rfx2 (e.g., intersect of RNAseq and ChIPseq data as outlined in Figure 2). Previous genomic analyses of Mcidas and Foxj1 in Xenopus MCCs did not include ChiPSeq data, so the dashed blue and green lines shown here indicate only that a gene’s transcription was upregulated in response to overexpression of mcidas or foxj1, respectively as per (Stubbs et al., 2008; Stubbs et al., 2012). Right panels (‘protein function and cell behavior’) illustrate mechanistic insights found here for MCCs by live imaging studies (Figures 3–7, Figure 4—figure supplements 2 and 3). Image published in: Chung MI et al. (2014) Copyright © 2013, Chung et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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