Xenbase Image ID: 148751

Fig. 5. The Syntabulin maternal depletion phenotype is rescued by sybu mRNA or by β-catenin mRNA. (A) Expression of the neural plate marker Sox2 in wild type early neurula embryos, n=16/16. (B) Syntabulin maternal depletion eliminated almost all Sox2 expression, with the exception of a weak residual ring of expression around the blastopore (inset, arrowhead), n=15/15. (C) Injection of β-catenin mRNA at 4-cell stage efficiently rescued expression of Sox2 in sybu depleted host transfer embyos, n=12/12. (D–G) The sybu AS ventralized phenotype was rescued both by syntabulin-UTR+ mRNA (n=7) and by β-catenin mRNA (n=12) at the tailbud stage. Image published in: Colozza G and De Robertis EM (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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