Xenbase Image ID: 148752

Fig. 6. Rescue of D-V patterning genes in Syntabulin-depleted embryos by syntabulin or β-catenin mRNA injection. (A) Expression of the Spemann organizer marker chordin (n=13/13) in wild type embryos at stage 10. (B) Chordin is eliminated by maternal depletion of syntabulin (n=9/9). (C) Injection of sybu mRNA partially rescues its own depletion (n=6/10), demonstrating specificity of the knock-down. (D) chordin expression is rescued, and somewhat expanded with respect to wild type, by β-catenin mRNA (n=14/14). (E–H) Maternal depletion of syntabulin increases expression of the ventral marker sizzled and this is counteracted by the injection of syntabulin-UTR+ or β-catenin mRNAs. Image published in: Colozza G and De Robertis EM (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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