Xenbase Image ID: 148958

Fig. 4. Secondary heart formation is lost in UV-ventralised hosts. (A, B) GATA4 injected reaggreagates (CAG-GFP) were transplanted at stage 20 in control (A, A′) or UV-treated hosts (B, B′) at the same stage. Transplants were viable (A′, B′) and were also positive for GFP expression in both control and UV-transplants analysed at stage 39. (C, D) Double-WMISH analysis for the expression of myl7 and myl3 indicated that whilst control transplants showed patterned expression of both myl7 and myl3 markers (C), transplants in UV-hosts (D) only expressed myl7 expression (white arrowhead). (C′, D′). Higher magnification of transplants shown in C and D. Region of overlap between myl3 and myl7 (purple) is indicated by black arrowhead. h, heart; ih, interhyoid muscle of the jaw; t, transplant; v, ventricle. The scale bar corresponds to 100 μm. Image published in: Caporilli S and Latinkic BV (2016) © 2016 The Authors. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

Return to previous page