Xenbase Image ID: 149406

Fig. 6 Inhibition of Notch signalling results in loss of segment formation in Xenopus embryos. a–f DAPT treatment did not affect the expression pattern of Gsc (a n = 42, 93 %; b n = 38, 87 %) and Brachyury (c n = 20, 95 %; d n = 14, 94 %), whereas it disrupted the paired-stripe expression pattern of Delta-2 (e n = 33, 100 %; f n = 47, 51 %). a–b Anterior views with dorsal side up. c–f Dorsal views with the anterior side up. g–h DAPT treatment resulted in loss of segmental expression of Mrf1 in amphioxus (g n = 12, 100 %; h n = 11, 100 %. Dorsal views with anterior to the left), MyoD in Xenopus (i n = 23, 100 %; j n = 15, 93 %), and Tbx1 (k n = 23, 100 %; l n = 13, 54 %). i, j The lower left panel displays the magnification of the somite expression of MyoD Image published in: Onai T et al. (2015) © Onai et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue gsc.L goosecoid, gsc-a, gsc-b, Xgsc X. laevis Throughout NF stage 12 prechordal plate tbxt.L bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury X. laevis Throughout NF stage 14 mesoderm circumblastoporal collar dlc.L delta-2, delta2, dll3, x-delta-2, X-Delta2 X. laevis Throughout NF stage 14 presomitic mesoderm caudal presomitic mesoderm myod1.L mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 28 myotome muscle tbx1.L cafs, cthm, dgcr, dorv, tbx1-a, tbx1-b, tbx1c, vcfs, xtbx1 X. laevis Throughout NF stage 28 pharyngeal arch mandibular arch hyoid arch branchial arch otic vesicle Image source: Published Larger Image Printer Friendly View

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