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Figure S11. Hydrodynamic modelling of Noggins diffusivity. (a) Solvent accessible surfaces of Noggin1, Noggin4 and EGFP-Noggin4 molecules were predicted by homological modelling and molecular dynamic equilibration. C2 symmetry axis (dashed line) passes through the interdimeric connection. Fused EGFP molecules are framed by rectangles. (b) Calculated diffusivity of the Noggin4-EGFP dimer in dependence of solvent viscosity. Viscosity values for water (at 300 K), blood3 and protoplasm4 were selected as calibration points. Image published in: Eroshkin FM et al. (2016) Copyright © 2016, Macmillan Publishers Limited. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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