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XB-IMG-150103

Xenbase Image ID: 150103


Fig. 6. BMP inhibition prevents the intercalation of MCCs, ionocytes and SSCs in the outer layer of the developing Xenopus epidermis. (A-E′) Sectioning through the epidermis at stage 25 revealed that in the BMP MO-injected embryos the supernumerary α-tubulin-positive MCCs (red in A-C′) and v1a-positive ionocytes (red in D-E′) fail to intercalate into the epidermis outer layer. (I-J′) Likewise, the supernumerary tph1-positive SSCs failed to intercalate in stage 35 BMP morphants (red in I-J′). (F-H′,K-M′) Even at later developmental stages, most of the supernumerary MCCs, which expressed the differentiation marker acetylated tubulin (white), were unable to intercalate properly into the outer layer.

Image published in: Cibois M et al. (2015)

Copyright © 2015. Image reproduced on Xenbase with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

GeneCloneSynonymsSpeciesStage(s)Tissue
tuba4b.L tuba4, alpha tubulin, alpha-tubulin, tuba4aX.laevisThroughout NF stage 25multiciliated cell
epidermis
epidermis outer layer
tuba4b.L tuba4, alpha tubulin, alpha-tubulin, tuba4aX.laevisThroughout NF stage 35 and 36multiciliated cell
epidermis
epidermis outer layer
tuba4b.L tuba4, alpha tubulin, alpha-tubulin, tuba4aX.laevisThroughout NF stage 40multiciliated cell
epidermis
epidermis outer layer
tph1.L X.laevisThroughout NF stage 35 and 36epidermis
epidermis outer layer
secretory epithelial cell
atp6v1a.L ho68, va68, vpp2, vma1, atp6a1, atp6v1a1, v1a, atpv1aX.laevisThroughout NF stage 25epidermis
ionocyte

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