Xenbase Image ID: 150109

Figure S4: The BMP and Notch pathways interact. Co-injection of mRNAs coding for a constitutively active form of the BMP receptor Alk3 (CA-Alk3) and a dominant negative form of the transcriptional Notch effector Suppressor-of-hairless (Su(H)DBM) (C) mitigated both the loss of -tubulin positive cells resulting from expression of CA-Alk3 alone (B) and their increase following injection of Su(H)DBM alone (D). Co-injection of mRNAs coding for a dominant negative form of the BMP receptor Alk3 (DN-Alk3) and a constitutively active form of the transcriptional Notch effector Suppressor-of-hairless (Su(H)Ank) (F) mitigated both the increase in -tubulin positive cells resulting from expression of DN-Alk3 alone (E) and their loss following injection of Su(H)Ank alone (G). The number of embryos showing the phenotype displayed over the total number of embryos examined is indicated. Image published in: Cibois M et al. (2015) Copyright © 2015. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tuba4b.L alpha tubulin, alpha-tubulin, tuba4, tuba4a X. laevis Sometime during NF stage 9 to NF stage 15 multiciliated cell epidermis Image source: Published Larger Image Printer Friendly View

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