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Fig. 2. Comparison of Illumina-Solexa (RNA-Seq) and Affymetrix microarray methods for detection of Xenopus orthologues for OMIM® deafness and vestibular disorder genes. Bar graphs compare detection data for 131 deafness only OMIM® genes (a), 28 vestibular disorder only OMIM® genes (b), 31 OMIM® genes that are associated with both vestibular and deafness phenotypes (c) and all 190 OMIM® genes (d) that met alignment criteria for both microarray and RNA-Seq analysis. Both technologies met expression criteria for 108 (57 %) of the 190 OMIM® genes. RNA-Seq met expression criteria for 48 (25 %) additional OMIM® genes not detected by microarray. Eleven (6 %) genes were detected by microarray methods only. Expression criteria were not met with either technology for 23 (12 %) of the 190 Xenopus OMIM® orthologues that met alignment criteria Image published in: Ramírez-Gordillo D et al. (2015) © Ramírez-Gordillo et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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