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Fig 7. Analysis of bimodal G-V relations from Kv1.2 FRAKT, Kv1.2 G329T and ΔT1-Kv1.2 FRAKT.(A) Best-fit double Boltzmann parameters (V1/2,1, z1, Gmax,1, V1/2,2, z2, Gmax,2) and Vmed from individual paired measurements before (Ctr) and after exposure to 1 mM sevoflurane (Sevo). Each pair of symbols connected by a solid line represents an individual paired experiment (Materials and Methods). The Gmax graphs depict raw values before normalization (in mS). The P value resulting from a paired Student-t test is shown above each graph, and the red marks indicate the mean values of the sample. (B)–(C) are as described for panel A. The number oocytes examined for each Kv channel was 6, 4, 5, respectively. Image published in: Liang Q et al. (2015) Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |