Xenbase Image ID: 151514

Figure 6. Semicircular canals increase in size during Xenopus larval development. A–D, Photomicrographs of the left otic capsule, viewed dorsally from developmental stages 46–49, illustrate the increase in dimensions of the horizontal semicircular canal. Black arrows in A–D indicate the location where the canal lumen radii were measured. Superimposed in D is a schematic illustrating the parameters used to determine circuit and lumen radii. E, Plot of horizontal canal lumen and circuit radius (mean ± SD) at different developmental stages before and after aVOR onset. Parameters before (stage 47) and after aVOR onset (stage 48) were significantly different (**p ≤ 0.01, Mann–Whitney U test); numbers of specimens used for the analysis at each stage are indicated in E. The scale bar in D applies to A–C. Ant, Anterior; Amp, ampulla; Lag, lagena; Ra, Rb, large and small axes of canal circuit radius, respectively; r, radius of canal lumen; Sac, saccule. Other abbreviations are the same as in Figure 1. Image published in: Lambert FM et al. (2008) Copyright © 2008. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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