Xenbase Image ID: 151649

Fig. 7. Adprhl1 protein can localize to the cardiac sarcomeres.A-E: Expression of human ADPRHL1 protein within a cluster of ventricular cells from a stage 48 Tg[myl7:(FLAG)human ADPRHL1] transgenic tadpole. A: Anti-FLAG. B: Phalloidin actin stain. C: Channel merge, including DAPI. D, E: Red rectangles (A) denote the position of 22 μm lengths of individual myofibrils. Human ADPRHL1 localizes to two stripes either side of the Z-disc (green arrowheads) and to the H-zone (white arrowheads). F-I: Similar localization of FLAG-Xenopus Adprhl1 within a cell of a stage 42 Tg[myl7:Gal4] plus Tg[UAS:(FLAG)Xenopus adprhl1] ventricle. F: Anti-FLAG. G: Phalloidin. H: Channel merge. I: Anti-FLAG, detail of the 13 μm red square (F). Z-disc (red arrowheads). Scale bars = 10 μm. Image published in: Smith SJ et al. (2016) © 2016 The Authors. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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