XB-IMG-151763
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Fig. 6. BMP signaling regulates foregut identity while Wnt/JNK signaling is necessary for both foregut identity and morphology (A–E) Confocal immunostaining of phosphorylated JNK (pJNK) or (F–J) phosphorylated Smad1/5/8 (pSmad1) in the foregut of bisected embryos at stage NF19. Quantification showed in Supplemental Fig. S7 (K–O) Confocal immunostaining of cortical β-catenin as cell membrane marker to show foregut cell morphology at NF19. (P–T) In situ hybridization with hhex in bisected NF19 embryos. The number of embryos with representative phenotype on the left versus total embryos examined on the right. Image published in: Zhang Z et al. (2016) Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives license
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