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Xenbase Image ID: 151779

Fig. 4. Xenopus and mouse Prdm12, but not amphioxus Prdm12, downregulate dbx1, nkx6-1 and nkx6-2, and induces en1 in Xenopus. (A-F) Transverse sections at the neural tube of stage 32 embryos injected unilaterally with mPrdm12 mRNA (200 pg/blastomere) and hybridized with indicated probes. The decrease of dbx1, nkx6-1, nkx6-2 and evx1 is indicated by arrows. IS, injected side. (G-J) RT-PCR analysis of the expression of indicated genes in RA-treated neuralized animal caps isolated from embryos injected with mouse Prdm12 mRNA (50 or 250 pg/blastomere), amphioxus Prdm12 and chimeric constructs mRNA (250 pg/blastomere) as indicated. In G and H, expression levels were compared with the expression level of uninjected caps, defined as 1.

Image published in: Thélie A et al. (2015)

Copyright © 2015. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

nkx6-2.Lnkx6.2X.laevisThroughout NF stage 32spinal cord
en1.Lxen1, en-1, engrailed-1, engrailed 1, eng1, en1-a, en1-bX.laevisThroughout NF stage 32spinal cord
pax6.LXLPAX6, xpax6, pax-6, an2, mgda, wagr, pax6-a, pax6-bX.laevisThroughout NF stage 32spinal cord
nkx6-1.Lnkx6.1X.laevisThroughout NF stage 32spinal cord
evx1.LXhox3, eve1X.laevisThroughout NF stage 32spinal cord
dbx1.SXdbx, dbxX.laevisThroughout NF stage 32spinal cord

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