XB-IMG-151779
Xenbase Image ID: 151779
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Fig. 4. Xenopus and mouse Prdm12, but not amphioxus Prdm12, downregulate dbx1, nkx6-1 and nkx6-2, and induces en1 in Xenopus. (A-F) Transverse sections at the neural tube of stage 32 embryos injected unilaterally with mPrdm12 mRNA (200 pg/blastomere) and hybridized with indicated probes. The decrease of dbx1, nkx6-1, nkx6-2 and evx1 is indicated by arrows. IS, injected side. (G-J) RT-PCR analysis of the expression of indicated genes in RA-treated neuralized animal caps isolated from embryos injected with mouse Prdm12 mRNA (50 or 250 pg/blastomere), amphioxus Prdm12 and chimeric constructs mRNA (250 pg/blastomere) as indicated. In G and H, expression levels were compared with the expression level of uninjected caps, defined as 1. Image published in: Thélie A et al. (2015) Copyright © 2015. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
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