Xenbase Image ID: 151781

Fig. 6. dbx1 and nkx6 overexpression blocks Prdm12 activity, and their knockdown upregulates En1. (A) RT-PCR analysis of en1 in neuralized animal caps overexpressing mouse Prdm12 mRNA (250 pg/blastomere), dbx1, dbx2, nkx6-1 or nkx6-2 mRNA (50 and 250 pg/blastomere) and treated with RA as indicated. (B) RT-PCR analysis of en1 and prdm12 in neuralized animal caps derived from embryos injected with MO against dbx1, nkx6-1 and nkx6-2 as indicated. Image published in: Thélie A et al. (2015) Copyright © 2015. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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