XB-IMG-151884
Xenbase Image ID: 151884
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Fig. 3. Alignment of the partial deduced amino acid sequence of the Xenopus integrin a2 subunit (xa2, GenBank accession number L43058) and the
corresponding segment of the human integrin a2 subunit (ha2, GenBank accession number X17033; Takada and Hemler, 1989). Also aligned is the sequence
deduced from a PCR amplified segment of the a2 subunit prepared from Xenopus embryonic stage 17 cDNA template (PCR2, GenBank accession number
L10186; Whittaker and DeSimone, 1993). Regions of identity with the xa2 sequence are indicated by hyphens. Gaps in the alignments are indicated by dots.
Amino acid numbering corresponds to the complete human a2 sequence (Takada and Hemler, 1989). Conserved cysteines (C) in the extracellular domain of
xa2 are indicated in bold; an additional cysteine in xa2 is underlined (C). Potential N-linked carbohydrate addition sites in the extracellular domain of xa2
are indicated by bold dots. The putative metal-binding domains are shaded and the predicted transmembrane domain boxed. The C-terminal peptide used for
antibody production is indicated by the double underline. Image published in: Meng F et al. (1997) Copyright © 1997. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |