Xenbase Image ID: 152142

Supp. Fig. S1. Analysis of the genomic locus surrounding X. tropicalis fgf genes. A: Synteny of fgf 2, fgf3, fgf4, fgf19, fgf6, and fgf23 were analysed for human, mouse, and Xenopus tropicalis. Chromosomal loci were constructed from Metazome (http://www.metazome.net/) showing the high level of conservation of the gene loci surrounding fgf genes. For each alignment, boxes with the same colour correspond to the same gene; white boxes correspond to genes without annotation or without orthologues in the species shown here. Hsa = Homo sapiens; Mmu = Mus musculus; and Xtr = Xenopus tropicalis. B: Identification of a partial sequence of fgf21. By synteny analysis, we have identified the region corresponding to the fgf21 locus in Xenopus tropicalis. We then used an EST for Xenopus laevis fgf21 (accession number EB470635) to identify the sequence in the X. tropicalis genome. This region of the genome contains numerous gaps (black boxes), which probably explain why we were unable to identify the full sequence. C: Identification of the genomic locus where fgf17 would be expected to be located. Our efforts to find X. tropicalis fgf17 were unsuccessful despite a fairly complete sequence around this region of the genome. Hsa = Homo sapiens; Mmu = Mus musculus; Xtr = Xenopus tropicalis. Image published in: Lea R et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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