Xenbase Image ID: 152274

Figure 7 14-3-3/14-3-3ς knockdown decreases phospho-XAC in retinal growth cones. (A, B) QIF analysis of pXAC (A) and XAC (B) in growth cones transfected with either R18K- or R18-YFP (n = no. of growth cones; four replicates; *p<0.05; Mann–Whitney). (C) Western blot of eye lysates showing 14-3-3ς knockdown with the antisense morpholino. a-Tubulin was used as a loading control. (D) QIF analysis of 14-3-3ς in growth cones injected with either control or 14-3-3ς morpholino (*** p<0.001; n = no. of growth cones; three replicates; unpaired t-test). (E, F) QIF analysis of pXAC (E) and XAC (F) in growth cones injected with control or 14-3-3ς morpholino (n = no of growth cones; *** p<0.001; three replicates; unpaired t-test). Image published in: Yoon BC et al. (2012) Copyright © 2012. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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